Histopathological study of dermal granuloma

INTRODUCTION:The objectives of this study were to confirm the diagnosis of clinically suspected dermal granuloma- tous diseases by histopathological examination and by routine and special stains as well as to study the incidence of various types of dermal granulomas.MATERIALS AND METHODS:This study was conducted at the Department of Pathology in collaboration with De- partment of Skin and Venereal disease. A total of 90 cases from outdoor patient department of skin and venereal disease, which were clinically diagnosed as suspected dermal granulomatous diseases, were taken as the study population.RESULTS:In our study, we found that leprosy had the highest incidence (50%), followed by cutaneous tuberculosis (30%) among all dermal granulomatous diseases like syphilis, fungal, granuloma annulare, foreign body, actino- mycosis, and sarcoidosis. Dermal granulomas were most common in middle age between 21 and 40 years of age.CONCLUSION:Histopathology played an important role in the final diagnosis of dermal granulomatous lesions. Most common dermal granulomatous disease was leprosy, followed by cutaneous tuberculosis.

Diagnosis of fat necrosis on FNAC – A case report.

Fine needle aspiration (FNA) of the breast has gained significant credibility in the diagnosis of breast diseases especially malignancy. Fat necrosis of the breast is a phenomenon that occurs within breast adipose tissue following exposure to trauma. It can mimic breast cancer clinically or radiologically. FNA of fat necrosis is a useful tool in directing management and treatment of the patients and avoiding unnecessary surgeries although histopathological examination is the gold standard for the final diagnosis.

Lessons in medical ethics from ancient Indian teachers.

Age of medicine is as old as the age of human on the earth. The doctor today is a scientist, technologist and healer at the same time. The ethics germane to the medical profession can’t be simple and uniform. Nor is the ethics simply a matter between the doctor and the patient; the society with its entire economic and political dimension is involved in much bigger way. Certain basic traditional thoughts given by ancient Indian teachers like Hippocrates, Charaka, Sushrutha and Vagbhata are still become relevant. Medical ethics in the medical curriculum, must be included not as a normative discipline but as a practical course with its own problems and considerations. As per Indian outlook, the role of ethics is certainly vast and varied, from treating a common cold, to the controversy on euthanasia, from the simple obligations of a family doctor, to the specialist services in the high cost, high technology five star nursing homes.

Demographic profile of Aluminium phosphide poisoning in Gandhinagar, Gujarat.

Background: Poisoning is an important cause of unnatural death, next to road traffic accidents in India even today. Incidence of aluminium phosphide poisoning is increasing day by day in western region of India including Gujarat. Demographic profile of aluminium phosphide poisoning cases is very helpful to be aware of current scenario and to implement preventive steps for betterment of health services. Objectives: The present study was undertaken to know the demographic profile of aluminium phosphide poisoning cases received as indoor or outdoor patient department of Gayatri Hospital, Gandhinagar, Gujarat, India. Material and methods: History taking, complete examination and necessary investigations of all cases of aluminium phosphide poisoning cases is very helpful to be aware of current scenario and to implement preventive steps for betterment of health services. Objectives: The present study was undertaken to know the demographic profile of aluminium phosphide poisoning cases received as indoor or outdoor patient department of Gayatri Hospital, Gandhinagar, Gujarat, India. Material and methods: History taking, complete examination and necessary investigations of all cases of aluminium phosphide poisoning was done, during the period of two years from 01-01-2012 prevalence of age and sex, socio-economic status, marital status, religion, literacy status, occupational status, time of consumption, manner of poisoning, reasons for suicidal consumption etc. Results: During the study period, 40 cases were diagnosed as of aluminium phosphide poisoning. Majority of the victims were in the age group of 41-50 years (25%), 70% were married, 80% were Hindu, 65% were of lower socio economical class and 57.5% belonged to rural area. Occurrence of aluminium phosphide poisoning was more common in evening time between 5 pm to 11 pm (45%) and among housewives (27.5%). Suicidal cases (82.5%) were more common compared to others. Conclusion: Based on these finding, preventive measures like restriction of sale and availability of aluminium phosphide, good availability of investigation and treatment, promoting poison information centre etc have been put forward.

Hb Q in India: An uncommon hemoglobin variant diagnosed in two patients â Case series.

Hemoglobin Q-India (α 64 Asp→His) is an important member of the hemoglobin Q family, molecularly characterized by the replacement of aspartic acid by histidine. The first case of Hb Q India was reported by Sukumaran in 1972 in a Sindhi family with associated β-halassemia. India is known as a country with a high prevalence of α - and β-thalassemia and different types of hemoglobinopathy. Many of these variants are yet to be identified. Here, we are reporting two cases of Hb Q- India diagnosed during premarital thalassemia screening.

Study of various cardiac arrhythmias in patients of acute myocardial infarction.

Background: Myocardial infarction is one of the major causes of sudden death in present era and cardiac arrhythmias are common complications of it. Material and methods: Present study was conducted at intensive coronary care unit (I.C.C.U) of tertiary care hospital, Ahmedabad on 100 cases of acute myocardial infarction to study the incidence of arrhythmia and their nature in relation with the site of infarction and to evaluate prognostic value of arrhythmias in Acute Myocardial Infraction (AMI). Results: Incidence of various arrhythmias was 76% in present study. S. tachycardia was more common (68%) than S. bradycardia (19%). S. tachycardia and tachyarrhythmia occurred more commonly with anterior wall myocardial infarction, while S. bradycardia and bradyarrhythmia with inferior wall myocardial infarction. Conclusion: Study of incidence of various cardiac arrhythmias, their nature and relation to site of infarction as well as prognostic value in patients of acute myocardial infarction proper treatment.

Nature helps to solve the crime â Diatoms study in case of drowning death.

Nature is everywhere surrounding us in different form. It includes single cell structure to extremely complex, living or non living, substance or creature. One of the important part of nature is diatom - submersion of body into water is known since ages. Diatoms study in case of drowing death is very useful for forensic investigators. It is one of the best example in which nature helps to solve the crime. In present article, we discussed about diatoms, diagnosis of drowning death and length of submersion of body in water with help of diatoms, collection, identification and preservation of diatoms for forensic analysis.

Forensic onychology: An essential entity against crime.

Forensic Onychology (Greek word, Onuks = nail, Logia = study of) is the subject which deals with study of fingernails and toenails for better administration of justice in the court of law. Identification means determination of individuality of a person. Nails are important tissues for human identification. One of the major advantages of utilizing nail is that, in comparison with other tissues, sample size and sampling process can be considered relatively non invasive and non destructive and yet each nail retains a discrete record of detailed information on genetic inheritance, drug use, pathology, diet and location history as well as exposure to explosives residues or other pollutants. In contrast to soft tissues, nails survive relatively well in the decomposition environment. Furthermore, in contrast to other long lasting tissues (such as bone and teeth) nails are easy to decontaminate from external sources of DNA. Thus examination of nail is very useful in many ways against crime. In this paper, we discussed about structure and method of analysis of nail, utility of examination, drug use and nails and detection of DNA from nails.

Fine needle aspiration cytology of swellings of head and neck region.

Head and neck mass lesions are frequently found in clinical practice. A spectrum of pathological lesions ranging from simple benign lesion to highly malignant manifestation is observed. Objectives: To make clinicopathological correlation of head and neck lesions and to assess the frequency of incidences of different sites, age groups, sex, and distribution among inflammation and neoplastic lesion. Materials and Methods: A retrospective study was conducted from January 2011 to April 2012. Fine-needle aspiration diagnosis was correlated with details of relevant clinical findings and investigations. Patients aged between 1 and 70 years were included in the study. A total of 200 patients with the swellings of head and neck underwent fine-needle aspiration cytology (FNAC). Results: Out of 200 fine-needle aspiration procedures, 52% were of thyroid, 28.50% were of lymph node, 11% from salivary gland, and 4% from soft tissue and miscellaneous swellings. There were 4.5% cases in which diagnosis was not possible. In inflammatory swelling (33%), tuberculous lymph node (42.12%) involvement is common than all other sites with male preponderance (55%). Conclusion: FNAC is a simple, quick, inexpensive, and minimally invasive technique to diagnose different types of head and neck swellings. It could differentiate the infective process from neoplastic one and avoids unnecessary surgeries. Thus, FNAC can be recommended as a first line of investigation in the diagnosis of head and neck swellings.